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Autoimmune Dysregulation and Purine Metabolism in Adenosine Deaminase Deficiency
Genetic defects in the adenosine deaminase (ADA) gene are among the most common causes for severe combined immunodeficiency (SCID). ADA-SCID patients suffer from lymphopenia, severely impaired cellular and humoral immunity, failure to thrive, and recurrent infections. Currently available therapeutic...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427915/ https://ncbi.nlm.nih.gov/pubmed/22969765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00265 |
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