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Altered self-assembly and apatite binding of amelogenin induced by N-terminal proline mutation

OBJECTIVE: A single Pro-70 to Thr (p.P70T) mutation of amelogenin is known to result in hypomineralized amelogenesis imperfecta (AI). This study aims to test the hypothesis that the given mutation affects the self-assembly of amelogenin molecules and impairs their ability to conduct the growth of ap...

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Библиографические подробности
Главные авторы: Zhu, Li, Uskoković, Vuk, Le, Thuan, DenBesten, Pamela, Huang, Yulei, Habelitz, Stefan, Li, Wu
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427771/
https://ncbi.nlm.nih.gov/pubmed/21081224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.archoralbio.2010.10.017
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