Lineage targeted MHC-II transgenic mice demonstrate the role of dendritic cells in bacterial driven colitis

BACKGROUND: Inflammatory bowel disease (IBD) pathogenesis involves an inadequately controlled immune reaction to intestinal microbiota and CD4(+) T cells, dependent upon MHC class II (MHC-II) processing and presentation by antigen presenting cells (APC), play important roles The role of professional...

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Hlavní autoři: Maggio-Price, Lillian, Seamons, Audrey, Bielefeldt-Ohmann, Helle, Zeng, Weiping, Brabb, Thea, Ware, Carol, Lei, Mingzu, Hershberg, Robert M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427724/
https://ncbi.nlm.nih.gov/pubmed/22619032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.23000
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