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forestSV: structural variant discovery through statistical learning

Detecting genomic structural variants from high-throughput sequencing data is a complex and unresolved challenge. We have developed a statistical learning approach, based on Random Forests, which integrates prior knowledge about the characteristics of structural variants and leads to improved discov...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Michaelson, Jacob J., Sebat, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427657/
https://ncbi.nlm.nih.gov/pubmed/22751202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2085
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