Biomarkers of hypothalamic–pituitary–adrenal axis activity in mice lacking 11β-HSD1 and H6PDH

Glucocorticoid concentrations are a balance between production under the negative feedback control and diurnal rhythm of the hypothalamic–pituitary–adrenal (HPA) axis and peripheral metabolism, for example by the enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which catalyses the reductio...

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Autors principals: Abrahams, Lianne, Semjonous, Nina M, Guest, Phil, Zielinska, Agnieszka, Hughes, Beverly, Lavery, Gareth G, Stewart, Paul M
Format: Artigo
Idioma:Inglês
Publicat: BioScientifica 2012
Matèries:
Regular Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427643/
https://ncbi.nlm.nih.gov/pubmed/22718432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-12-0178
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