Matrix Metalloproteinase-9 Genetic Polymorphisms and the Risk for Advanced Pelvic Organ Prolapse

OBJECTIVE: Matrix metalloproteinase-9 (MMP-9) is a protease associated with degradation of collagen and elastin. Because increased MMP-9 activity in vaginal tissue has been associated with pelvic organ prolapse, we sought to comprehensively estimate MMP-9 genetic variants and the risk for advanced p...

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Main Authors: Wu, Jennifer M., Visco, Anthony G., Grass, Elizabeth A., Craig, Damian M., Fulton, Rebekah G., Haynes, Carol, Weidner, Alison C., Shah, Svati H.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427536/
https://ncbi.nlm.nih.gov/pubmed/22914468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/AOG.0b013e318262234b
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