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Isolation of Q nucleoside precursor present in tRNA of an E. coli mutant and its characterization as 7-(cyano)-7-deazaguanosine.

One of the E. coli mutants selected for deficiency of modified nucleoside Q was found to contain an analogue of Q and normal guanosine in place of Q. The analogue of Q, designated as preQo, was isolated on a large scale from purified tRNATyr containing preQo. The structure of preQo was determined to...

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Autors principals: Noguchi, S, Yamaizumi, Z, Ohgi, T, Goto, T, Nishimura, Y, Hirota, Y, Nishimura, S
Format: Artigo
Idioma:Inglês
Publicat: 1978
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC342744/
https://ncbi.nlm.nih.gov/pubmed/364423
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