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A restricted cell population propagates glioblastoma growth following chemotherapy

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, with a median survival of about one year(1). This poor prognosis is due to therapeutic resistance and tumor recurrence following surgical removal. Precisely how recurrence occurs is unknown. Using a genetically-engineere...

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Detalhes bibliográficos
Main Authors: Chen, Jian, Li, Yanjiao, Yu, Tzong-Shiue, McKay, Renée M., Burns, Dennis K., Kernie, Steven G., Parada, Luis F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427400/
https://ncbi.nlm.nih.gov/pubmed/22854781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11287
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