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Measuring the Maturity of the Fast-Spiking Interneuron Transcriptional Program in Autism, Schizophrenia, and Bipolar Disorder

BACKGROUND: Emerging evidence suggests that fast-spiking (FS) interneurons are disrupted in multiple neuropsychiatric disorders including autism, schizophrenia, and bipolar disorder. FS cells, which are the primary source of synaptic inhibition, are critical for temporally organizing brain activity,...

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Main Authors: Gandal, Michael J., Nesbitt, Addie May, McCurdy, Richard M., Alter, Mark D.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427326/
https://ncbi.nlm.nih.gov/pubmed/22936973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041215
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