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Atmospheric Oxygen Tension Slows Myoblast Proliferation via Mitochondrial Activation

BACKGROUND: Mitochondrial activity inhibits proliferation and is required for differentiation of myoblasts. Myoblast proliferation is also inhibited by the ∼20% oxygen level used in standard tissue culture. We hypothesize that mitochondrial activity would be greater at hyperoxia (20% O(2)) relative...

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Hlavní autoři: Duguez, Stephanie, Duddy, William J., Gnocchi, Viola, Bowe, James, Dadgar, Sherry, Partridge, Terence A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427224/
https://ncbi.nlm.nih.gov/pubmed/22937109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043853
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