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Direct sampling of cystic fibrosis lungs indicates that DNA-based analyses of upper-airway specimens can misrepresent lung microbiota

Recent work using culture-independent methods suggests that the lungs of cystic fibrosis (CF) patients harbor a vast array of bacteria not conventionally implicated in CF lung disease. However, sampling lung secretions in living subjects requires that expectorated specimens or collection devices pas...

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Detalhes bibliográficos
Main Authors: Goddard, Amanda F., Staudinger, Benjamin J., Dowd, Scot E., Joshi-Datar, Amruta, Wolcott, Randall D., Aitken, Moira L., Fligner, Corinne L., Singh, Pradeep K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427132/
https://ncbi.nlm.nih.gov/pubmed/22872870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107435109
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