Lanean...

Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3

We have developed a targeted method to quantify all combinations of methylation on an H3 peptide containing lysines 27 and 36 (H3K27-K36). By using stable isotopes that separately label the histone backbone and its methylations, we tracked the rates of methylation and demethylation in myeloma cells...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zheng, Yupeng, Sweet, Steve M. M., Popovic, Relja, Martinez-Garcia, Eva, Tipton, Jeremiah D., Thomas, Paul M., Licht, Jonathan D., Kelleher, Neil L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427122/
https://ncbi.nlm.nih.gov/pubmed/22869745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205707109
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