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Rational, combinatorial, and genomic approaches for engineering L-tyrosine production in Escherichia coli
Although microbial metabolic engineering has traditionally relied on rational and knowledge-driven techniques, significant improvements in strain performance can be further obtained through the use of combinatorial approaches exploiting phenotypic diversification and screening. Here, we demonstrate...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427108/ https://ncbi.nlm.nih.gov/pubmed/22869698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206346109 |
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