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Strategies to alleviate original antigenic sin responses to influenza viruses

Original antigenic sin is a phenomenon wherein sequential exposure to closely related influenza virus variants reduces antibody (Ab) response to novel antigenic determinants in the second strain and, consequently, impairs the development of immune memory. This could pose a risk to the development of...

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Detalhes bibliográficos
Main Authors: Kim, Jin Hyang, Davis, William G., Sambhara, Suryaprakash, Jacob, Joshy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427092/
https://ncbi.nlm.nih.gov/pubmed/22869731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912458109
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