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Atomic structure of the vimentin central α-helical domain and its implications for intermediate filament assembly

Together with actin filaments and microtubules, intermediate filaments (IFs) are the basic cytoskeletal components of metazoan cells. Over 80 human diseases have been linked to mutations in various IF proteins to date. However, the filament structure is far from being resolved at the atomic level, w...

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Main Authors: Chernyatina, Anastasia A., Nicolet, Stefan, Aebi, Ueli, Herrmann, Harald, Strelkov, Sergei V.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427084/
https://ncbi.nlm.nih.gov/pubmed/22869704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206836109
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