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Tumor suppressor Hippo/MST1 kinase mediates chemotaxis by regulating spreading and adhesion
Chemotaxis depends on a network of parallel pathways that coordinate cytoskeletal events to bias cell movement along a chemoattractant gradient. Using a forward genetic screen in Dictyostelium discoideum, we identified the Ste20 kinase KrsB, a homolog of tumor suppressors Hippo and MST1/2, as a nega...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427065/ https://ncbi.nlm.nih.gov/pubmed/22847424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211304109 |
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