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Quantitation of ten 30S ribosomal assembly intermediates using fluorescence triple correlation spectroscopy

The self-assembly of bacterial 30S ribosomes involves a large number of RNA folding and RNA-protein binding steps. The sequence of steps determines the overall assembly mechanism and the structure of the mechanism has ramifications for the robustness of biogenesis and resilience against kinetic trap...

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Autori principali: Ridgeway, William K., Millar, David P., Williamson, James R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427059/
https://ncbi.nlm.nih.gov/pubmed/22869699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204620109
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