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Treatment-Induced Bone Loss and Fractures in Cancer Patients Undergoing Hormone Ablation Therapy: Efficacy and Safety of Denosumab

Hormone ablation therapy (HALT) for breast or prostate cancer accelerates the development of osteoporosis in both men and women by causing estrogen deficiency, which increases the risk for fracture by promoting bone resorption mediated by osteoclasts. Denosumab, a fully human monoclonal antibody tha...

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Detalhes bibliográficos
Main Authors: Lipton, Allan, Smith, Matthew R., Ellis, Georgiana K., Goessl, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427033/
https://ncbi.nlm.nih.gov/pubmed/22933844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMO.S8511
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