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Bioinformatic Tools Identify Chromosome-Specific DNA Probes and Facilitate Risk Assessment by Detecting Aneusomies in Extra-embryonic Tissues

Despite their non-diseased nature, healthy human tissues may show a surprisingly large fraction of aneusomic or aneuploid cells. We have shown previously that hybridization of three to six non-isotopically labeled, chromosome-specific DNA probes reveals different proportions of aneuploid cells in in...

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Detalhes bibliográficos
Main Authors: Zeng, Hui, Weier, Jingly F, Wang, Mei, Kassabian, Haig J, Polyzos, Aris A, Baumgartner, Adolf, O’Brien, Benjamin, Weier, Heinz-Ulli G
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426778/
https://ncbi.nlm.nih.gov/pubmed/23450259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920212802510510
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