XB130 Mediates Cancer Cell Proliferation and Survival through Multiple Signaling Events Downstream of Akt

XB130, a novel adaptor protein, mediates RET/PTC chromosome rearrangement-related thyroid cancer cell proliferation and survival through phosphatidyl-inositol-3-kinase (PI3K)/Akt pathway. Recently, XB130 was found in different cancer cells in the absence of RET/PTC. To determine whether RET/PTC is r...

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Detalhes bibliográficos
Main Authors: Shiozaki, Atsushi, Shen-Tu, Grace, Bai, Xiaohui, Iitaka, Daisuke, De Falco, Valentina, Santoro, Massimo, Keshavjee, Shaf, Liu, Mingyao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426539/
https://ncbi.nlm.nih.gov/pubmed/22928011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043646
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