Histone deacetylase-4 is required during early cranial neural crest development for generation of the zebrafish palatal skeleton

BACKGROUND: Histone deacetylase-4 (Hdac4) is a class II histone deacetylase that inhibits the activity of transcription factors. In humans, HDAC4 deficiency is associated with non-syndromic oral clefts and brachydactyly mental retardation syndrome (BDMR) with craniofacial abnormalities. RESULTS: We...

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Hauptverfasser: DeLaurier, April, Nakamura, Yukio, Braasch, Ingo, Khanna, Vishesh, Kato, Hiroyuki, Wakitani, Shigeyuki, Postlethwait, John H, Kimmel, Charles B
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426487/
https://ncbi.nlm.nih.gov/pubmed/22676467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-12-16
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