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Studies on gene control regions. VI. The 5- methyl of thymine, a lac repressor recognition site.

Three site specific deoxyuridine analogs of lac operator were tested for binding with wild type (SQ) and tight binding (QX86) lac repressors. Insertion of uracil for thymine at site 13 (our nomenclature) significantly reduced the dissociation half-life of QX86 repressor for lac operator DNA (21 vs 1...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Goeddel, D V, Yansura, D G, Caruthers, M H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 1977
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC342633/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/333399/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/4.9.3039
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