FUNCTIONAL SIGNIFICANCE OF ISOFORM DIVERSIFICATION IN THE PROTOCADHERIN GAMMA GENE CLUSTER

The mammalian Protocadherin (Pcdh) alpha, beta, and gamma gene clusters encode a large family of cadherin-like transmembrane proteins that are differentially expressed in individual neurons. The 22 isoforms of the Pcdhg gene cluster are diversified into A-, B- and C-types, and the C-type isoforms di...

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Main Authors: Chen, Weisheng V., Alvarez, Francisco J., Lefebvre, Julie L., Friedman, Brad, Nwakeze, Chiamaka, Geiman, Eric, Smith, Courtney, Thu, Chan Aye, Tapia, Juan Carlos, Tasic, Bosiljka, Sanes, Joshua R., Maniatis, Tom
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426296/
https://ncbi.nlm.nih.gov/pubmed/22884324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.06.039
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