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Role of the inhibitory KIR ligand HLA-Bw4 and HLA-C expression levels in the recognition of leukemic cells by Natural Killer cells

Transplantation of acute myeloid leukemia (AML) patients with grafts from related haploidentical donors has been shown to result in a potent graft-versus-leukemia effect. This effect is mediated by NK cells because of the lack of activation of inhibitory killer cell immunoglobulin-like receptors (KI...

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Detalhes bibliográficos
Main Authors: Verheyden, Sonja, Ferrone, Soldano, Mulder, Arend, Claas, Frans H., Schots, Rik, De Moerloose, Barbara, Benoit, Yves, Demanet, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426282/
https://ncbi.nlm.nih.gov/pubmed/18841361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0601-7
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