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Dynamics and Visualization of MCF7 Adenocarcinoma Cell Death by Aptamer-C1q-Mediated Membrane Attack

This study was designed to characterize binding of a DNA aptamer to breast cancer cells and to test whether that aptamer could be used to kill target cells in vitro as part of an aptamer-C1q protein conjugate by coupling to the classic complement cascade. A biotinylated DNA aptamer designated MUC1-5...

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Detalhes bibliográficos
Main Authors: Stecker, John R., Savage, Alissa A., Bruno, John G., García, Dana M., Koke, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426207/
https://ncbi.nlm.nih.gov/pubmed/22861487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0355
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