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Chemical synthesis of the hexanucleotide d(A-C-C-A-G-C) required to isolate fibroin mRNA on an affinity column.

The synthesis of the hexanucleotide d)A-C-C-A-G-C), complementary to the 2 major triplets of fibroin mRNA, using the phosphotriester methodology is described. The protected dinucleotides ((MeO)2Tr)dbzA.anC, ((MeO)2Tr)danC.bzA and ((meO)2Tr)dacG.anC were synthesized; the latter two were detritylated...

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Detalles Bibliográficos
Autores principales: Cashion, P, Notman, H, Sathe, G, Cadger, T, Porter, K, Jay, E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1977
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC342594/
https://ncbi.nlm.nih.gov/pubmed/909785
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