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A Novel Mathematical Approach to Define the Genes/SNPs Conferring Risk or Protection in Sporadic Amyotrophic Lateral Sclerosis Based on Auto Contractive Map Neural Networks and Graph Theory

Background. Complex diseases like amyotrophic lateral sclerosis (ALS) implicate phenotypic and genetic heterogeneity. Therefore, multiple genetic traits may show differential association with the disease. The Auto Contractive Map (AutoCM), belonging to the Artificial Neural Network (ANN) architectur...

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Detalhes bibliográficos
Main Authors: Buscema, Massimo, Penco, Silvana, Grossi, Enzo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425858/
https://ncbi.nlm.nih.gov/pubmed/22934166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/478560
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