Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities

Extracellular ATP and ADP trigger inflammatory, vasodilatatory, and prothrombotic signaling events in the vasculature, and their turnover is governed by networks of membrane-associated enzymes. The contribution of soluble activities to intravascular nucleotide homeostasis remains controversial. By u...

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Bibliografski detalji
Glavni autori: Yegutkin, Gennady G., Wieringa, Bé, Robson, Simon C., Jalkanen, Sirpa
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2012
Teme:
Research Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425827/
https://ncbi.nlm.nih.gov/pubmed/22637533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-205658
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