Selection of Microsatellite Markers for Bladder Cancer Diagnosis without the Need for Corresponding Blood

Microsatellite markers are used for loss-of-heterozygosity, allelic imbalance and clonality analyses in cancers. Usually, tumor DNA is compared to corresponding normal DNA. However, normal DNA is not always available and can display aberrant allele ratios due to copy number variations in the genome....

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Main Authors: van Tilborg, Angela A. G., Kompier, Lucie C., Lurkin, Irene, Poort, Ricardo, El Bouazzaoui, Samira, van der Keur, Kirstin, Zuiverloon, Tahlita, Dyrskjot, Lars, Orntoft, Torben F., Roobol, Monique J., Zwarthoff, Ellen C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425555/
https://ncbi.nlm.nih.gov/pubmed/22927958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043345
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