Inhibitory Effect of mTOR Activator MHY1485 on Autophagy: Suppression of Lysosomal Fusion

Autophagy is a major degradative process responsible for the disposal of cytoplasmic proteins and dysfunctional organelles via the lysosomal pathway. During the autophagic process, cells form double-membraned vesicles called autophagosomes that sequester disposable materials in the cytoplasm and fin...

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Bibliographische Detailangaben
Hauptverfasser: Choi, Yeon Ja, Park, Yun Jung, Park, Ji Young, Jeong, Hyoung Oh, Kim, Dae Hyun, Ha, Young Mi, Kim, Ji Min, Song, Yu Min, Heo, Hyoung-Sam, Yu, Byung Pal, Chun, Pusoon, Moon, Hyung Ryong, Chung, Hae Young
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425474/
https://ncbi.nlm.nih.gov/pubmed/22927967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043418
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