Effects of Tocotrienol and Lovastatin Combination on Osteoblast and Osteoclast Activity in Estrogen-Deficient Osteoporosis

Statins are HMGCoA reductase inhibitors and had been demonstrated to stimulate bone formation in rodents after high oral doses. Observational studies on patients treated with oral statins were varied. Delta-tocotrienol had been found to stimulate the cleavage of HMGCoA reductase and inhibit its acti...

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Autori principali: Abdul-Majeed, Saif, Mohamed, Norazlina, Soelaiman, Ima-Nirwana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425381/
https://ncbi.nlm.nih.gov/pubmed/22927884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/960742
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