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Biosynthesis of the major brain gangliosides GD1a and GT1b

Gangliosides—sialylated glycosphingolipids—are the major glycoconjugates of nerve cells. The same four structures—GM1, GD1a, GD1b and GT1b—comprise the great majority of gangliosides in mammalian brains. They share a common tetrasaccharide core (Galβ1–3GalNAcβ1-4Galβ1-4Glcβ1-1′Cer) with one or two s...

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Autors principals: Sturgill, Elizabeth R, Aoki, Kazuhiro, Lopez, Pablo HH, Colacurcio, Daniel, Vajn, Katarina, Lorenzini, Ileana, Majić, Senka, Yang, Won Ho, Heffer, Marija, Tiemeyer, Michael, Marth, Jamey D, Schnaar, Ronald L
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425327/
https://ncbi.nlm.nih.gov/pubmed/22735313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cws103
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