Biosynthesis of the major brain gangliosides GD1a and GT1b

Gangliosides—sialylated glycosphingolipids—are the major glycoconjugates of nerve cells. The same four structures—GM1, GD1a, GD1b and GT1b—comprise the great majority of gangliosides in mammalian brains. They share a common tetrasaccharide core (Galβ1–3GalNAcβ1-4Galβ1-4Glcβ1-1′Cer) with one or two s...

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Bibliographic Details
Main Authors: Sturgill, Elizabeth R, Aoki, Kazuhiro, Lopez, Pablo HH, Colacurcio, Daniel, Vajn, Katarina, Lorenzini, Ileana, Majić, Senka, Yang, Won Ho, Heffer, Marija, Tiemeyer, Michael, Marth, Jamey D, Schnaar, Ronald L
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425327/
https://ncbi.nlm.nih.gov/pubmed/22735313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cws103
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