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Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker

BACKGROUND: Germinal center kinase-like kinase (GLK, also termed MAP4K3), a member of the MAP4K family, may regulate gene transcription, apoptosis and immune inflammation in response to extracellular signals. The enhanced expression of GLK has been shown to correspond with disease severity in patien...

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Detalhes bibliográficos
Main Authors: Chen, Der-Yuan, Chuang, Huai-Chia, Lan, Joung-Liang, Chen, Yi-Ming, Hung, Wei-Ting, Lai, Kuo-Lung, Tan, Tse-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424974/
https://ncbi.nlm.nih.gov/pubmed/22867055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-10-84
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