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LIN28 Is Selectively Expressed by Primordial and Pre-Meiotic Germ Cells in the Human Fetal Ovary

Germ cell development requires timely transition from primordial germ cell (PGC) self-renewal to meiotic differentiation. This is associated with widespread changes in gene expression, including downregulation of stem cell–associated genes, such as OCT4 and KIT, and upregulation of markers of germ c...

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Detalhes bibliográficos
Main Authors: Childs, Andrew J., Kinnell, Hazel L., He, Jing, Anderson, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424972/
https://ncbi.nlm.nih.gov/pubmed/22296229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2011.0730
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