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Multicomponent Assembly of Proposed DNA Precursors in Water

[Image: see text] We propose a novel pathway for the prebiotic synthesis of 2′-deoxynucleotides. Consideration of the constitutional chemical relationships between glycolaldehyde and β-mercapto-acetaldehyde, and the corresponding proteinogenic amino acids, serine and cysteine, led us to explore the...

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Detalhes bibliográficos
Main Authors: Powner, Matthew W., Zheng, Shao-Liang, Szostak, Jack W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424849/
https://ncbi.nlm.nih.gov/pubmed/22839703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja306176n
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