Intrinsic oscillatory activity arising within the electrically coupled AII amacrine–ON cone bipolar cell network is driven by voltage-gated Na(+) channels

In the rd1 mouse model for retinal degeneration, the loss of photoreceptors results in oscillatory activity (∼10–20 Hz) within the remnant electrically coupled network of retinal ON cone bipolar and AII amacrine cells. We tested the role of hyperpolarization-activated currents (I(h)), voltage-gated...

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Detalhes bibliográficos
Main Authors: Trenholm, Stuart, Borowska, Joanna, Zhang, Jiawei, Hoggarth, Alex, Johnson, Kyle, Barnes, Steven, Lewis, Timothy J, Awatramani, Gautam B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Neuroscience: Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424767/
https://ncbi.nlm.nih.gov/pubmed/22393249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.225060
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