Lactate flux in astrocytes is enhanced by a non-catalytic action of carbonic anhydrase II

Rapid exchange of metabolites between different cell types is crucial for energy homeostasis of the brain. Besides glucose, lactate is a major metabolite in the brain and is primarily produced in astrocytes. In the present study, we report that carbonic anhydrase 2 (CAII) enhances both influx and ef...

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Hlavní autoři: Stridh, Malin H, Alt, Marco D, Wittmann, Sarah, Heidtmann, Hella, Aggarwal, Mayank, Riederer, Brigitte, Seidler, Ursula, Wennemuth, Gunther, McKenna, Robert, Deitmer, Joachim W, Becker, Holger M
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2012
Témata:
Neuroscience: Cellular/Molecular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424756/
https://ncbi.nlm.nih.gov/pubmed/22451434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.220152
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