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Studies of gene control regions. III. Binding of synthetic and modified synthetic lac operator DNAs to lactose repressor.

Chemically synthesized lactose operator DNA was tested for binding with lactose repressor protein. These operator DNAs were found to (1) bind specifically to lactose SQ repressor as measured by release of binding with the inducing ligand isopropyl-beta-D-thiogalactoside, (2) have dissociation half-l...

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Detalhes bibliográficos
Main Authors: Yansura, D G, Goeddel, D V, Cribbs, D L, Caruthers, M H
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC342475/
https://ncbi.nlm.nih.gov/pubmed/866187
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