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Studies of gene control regions. III. Binding of synthetic and modified synthetic lac operator DNAs to lactose repressor.

Chemically synthesized lactose operator DNA was tested for binding with lactose repressor protein. These operator DNAs were found to (1) bind specifically to lactose SQ repressor as measured by release of binding with the inducing ligand isopropyl-beta-D-thiogalactoside, (2) have dissociation half-l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yansura, D G, Goeddel, D V, Cribbs, D L, Caruthers, M H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1977
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC342475/
https://ncbi.nlm.nih.gov/pubmed/866187
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