Kv1.1-dependent control of hippocampal neuron number as revealed by mosaic analysis with double markers

Megencephaly, or mceph, is a spontaneous frame-shift mutation of the mouse Kv1.1 gene. This mceph mutation results in a truncated Kv1.1 channel α-subunit without the channel pore domain or the voltage sensor. Interestingly, mceph/mceph mouse brains are enlarged and – unlike wild-type mouse brains –...

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Detalhes bibliográficos
Main Authors: Yang, Shi-Bing, Mclemore, Kellan D, Tasic, Bosiljka, Luo, Liqun, Jan, Yuh Nung, Jan, Lily Yeh
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
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Special Section Related Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424722/
https://ncbi.nlm.nih.gov/pubmed/22411008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.228486
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