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Kv1.1-dependent control of hippocampal neuron number as revealed by mosaic analysis with double markers
Megencephaly, or mceph, is a spontaneous frame-shift mutation of the mouse Kv1.1 gene. This mceph mutation results in a truncated Kv1.1 channel α-subunit without the channel pore domain or the voltage sensor. Interestingly, mceph/mceph mouse brains are enlarged and – unlike wild-type mouse brains –...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424722/ https://ncbi.nlm.nih.gov/pubmed/22411008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.228486 |
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