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How the Hodgkin–Huxley equations inspired the Cardiac Physiome Project

Early modelling of cardiac cells (1960–1980) was based on extensions of the Hodgkin–Huxley nerve axon equations with additional channels incorporated, but after 1980 it became clear that processes other than ion channel gating were also critical in generating electrical activity. This article review...

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Hlavní autoři: Noble, Denis, Garny, Alan, Noble, Penelope J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424720/
https://ncbi.nlm.nih.gov/pubmed/22473779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.224238
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