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A high-throughput next-generation sequencing-based method for detecting the mutational fingerprint of carcinogens
Many carcinogens leave a unique mutational fingerprint in the human genome. These mutational fingerprints manifest as specific types of mutations often clustering at certain genomic loci in tumor genomes from carcinogen-exposed individuals. To develop a high-throughput method for detecting the mutat...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424585/ https://ncbi.nlm.nih.gov/pubmed/22735701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks610 |
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