A new way of measuring apoptosis by absolute quantitation of inter-nucleosomally fragmented genomic DNA

Several critical events of apoptosis occur in the cell nucleus, including inter-nucleosomal DNA fragmentation (apoptotic DNA) and eventual chromatin condensation. The generation of apoptotic DNA has become a biochemical hallmark of apoptosis because it is a late ‘point of no return’ step in both the...

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Autori principali: Hooker, David J., Mobarok, Masqura, Anderson, Jenny L., Rajasuriar, Reena, Gray, Lachlan R., Ellett, Anne M., Lewin, Sharon R., Gorry, Paul R., Cherry, Catherine L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Methods Online
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424536/
https://ncbi.nlm.nih.gov/pubmed/22544708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks334
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