Gelsolin Induces Colorectal Tumor Cell Invasion via Modulation of the Urokinase-Type Plasminogen Activator Cascade

Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and therapy-resistance. In vitro, gelsolin has anti-apop...

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Autori principali: Zhuo, Jingli, Tan, Ee Hong, Yan, Benedict, Tochhawng, Lalchhandami, Jayapal, Manikandan, Koh, Shiuan, Tay, Hwee Kee, Maciver, Sutherland K., Hooi, Shing Chuan, Salto-Tellez, Manuel, Kumar, Alan Prem, Goh, Yaw Chong, Lim, Yaw Chyn, Yap, Celestial T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424201/
https://ncbi.nlm.nih.gov/pubmed/22927998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043594
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