Relationship between plasma high mobility group box-1 protein levels and clinical outcomes of aneurysmal subarachnoid hemorrhage

BACKGROUND: High-mobility group box 1 (HMGB1), originally described as a nuclear protein that binds to and modifies DNA, is now regarded as a central mediator of inflammation by acting as a cytokine. However, the association of HMGB1 in the peripheral blood with disease outcome and cerebrovasospasm...

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Bibliografiske detaljer
Main Authors: Zhu, Xiang-Dong, Chen, Jing-Sen, Zhou, Feng, Liu, Qi-Chang, Chen, Gao, Zhang, Jian-Min
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424135/
https://ncbi.nlm.nih.gov/pubmed/22883976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-194
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