IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy

Preeclampsia is associated with autoimmune cells T(H)17, secreting interleukin-17, autoantibodies activating the angiotensin II type I receptor (AT1-AA), and placental oxidative stress (ROS). The objective of our study was to determine whether chronic IL-17 increases blood pressure by stimulating RO...

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Hlavní autoři: Dhillion, Pushpinder, Wallace, Kedra, Herse, Florian, Scott, Jeremy, Wallukat, Gerd, Heath, Judith, Mosely, Janae, Martin, James N., Dechend, Ralf, LaMarca, Babbette
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423993/
https://ncbi.nlm.nih.gov/pubmed/22718806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00051.2012
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