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RNA Interference Trigger Variants: Getting the Most Out of RNA for RNA Interference-Based Therapeutics
The manifestation of RNA interference (RNAi)-based therapeutics lies in safe and successful delivery of small interfering RNAs (siRNAs), the molecular entity that triggers and guides sequence-specific degradation of target mRNAs. Optimizing the chemistry and structure of siRNAs to achieve maximum ef...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Mary Ann Liebert, Inc.
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3423874/ https://ncbi.nlm.nih.gov/pubmed/22703279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0361 |
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