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RNA Interference Trigger Variants: Getting the Most Out of RNA for RNA Interference-Based Therapeutics

The manifestation of RNA interference (RNAi)-based therapeutics lies in safe and successful delivery of small interfering RNAs (siRNAs), the molecular entity that triggers and guides sequence-specific degradation of target mRNAs. Optimizing the chemistry and structure of siRNAs to achieve maximum ef...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Snead, Nicholas M., Rossi, John J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423874/
https://ncbi.nlm.nih.gov/pubmed/22703279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0361
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