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Improved throughput traction microscopy reveals pivotal role for matrix stiffness in fibroblast contractility and TGF-β responsiveness

Lung fibroblast functions such as matrix remodeling and activation of latent transforming growth factor-β1 (TGF-β1) are associated with expression of the myofibroblast phenotype and are directly linked to fibroblast capacity to generate force and deform the extracellular matrix. However, the study o...

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Main Authors: Marinković, Aleksandar, Mih, Justin D., Park, Jin-Ah, Liu, Fei, Tschumperlin, Daniel J.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423859/
https://ncbi.nlm.nih.gov/pubmed/22659883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00108.2012
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