Loss of heterozygosity of CDKN2A (p16INK4a) and RB1 tumor suppressor genes in testicular germ cell tumors

BACKGROUND: Testicular germ cell tumors (TGCTs) are the most frequent malignances in young adult men. The two main histological forms, seminomas and nonseminomas, differ biologically and clinically. pRB protein and its immediate upstream regulator p16INK4a are involved in the RB pathway which is der...

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Main Authors: Vladusic, Tomislav, Hrascan, Reno, Pecina-Slaus, Nives, Vrhovac, Ivana, Gamulin, Marija, Franekic, Jasna, Kruslin, Bozo
Format: Artigo
Jezik:Inglês
Izdano: Versita, Warsaw 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423692/
https://ncbi.nlm.nih.gov/pubmed/22933911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/v10019-010-0035-7
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