Stable Inhibition of Specific Estrogen Receptor α (ERα) Phosphorylation Confers Increased Growth, Migration/Invasion, and Disruption of Estradiol Signaling in MCF-7 Breast Cancer Cells

Elevated phosphorylation of estrogen receptor α (ERα) at serines 118 (S118) and 167 (S167) is associated with favorable outcome for tamoxifen adjuvant therapy and may serve as surrogate markers for a functional ERα signaling pathway in breast cancer. It is possible that loss of phosphorylation at S1...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Huderson, B. P., Duplessis, T. T., Williams, C. C., Seger, H. C., Marsden, C. G., Pouey, K. J., Hill, S. M., Rowan, B. G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2012
Pynciau:
Cancer-Oncogenes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423624/
https://ncbi.nlm.nih.gov/pubmed/22733972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-2001
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